Quoted By:
Think of a main game region.
Got it?
Sure you've got it?
You have now been tasked with directing a sequel to that region's game, not unlike BW -> B2W2.
What do you do? Any changes to the region? Do you traverse it a different way? What villains might the player encounter? What gym leaders or Elite Four members might they encounter?
Answer as many as you like in as much detail as you like.