>>52638687Two factors, in anime you're a third person always (being the main focus of any interaction distresses us greatly), and their expressions, as their facial features as a whole, are exaggerated.
Autistic people are good at analyzing things that happen in real life, it's just that when we are the focus, we drop all the spaghetti and can't proccess anything right.
For instance, I was able to catch on that my mother's friend's son was a sociopath since he was a kid and I was a teenager, and I told my mother about that. Now, almost 20 years later, he was clinically diagnosed as such.