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Scientists speculate that Shiinotic evolved their extremely efficient knockout spores due to being frequently fed on by Nidorina in the distant past. More recently, some colonies of Nidorina seem to have grown somewhat resistant to Shiinotic spores; instead of falling asleep the Nidorina are set upon by various kinds of sensory hallucinations. Curiously, some individual Nidorina seem to purposefully seek Shiinotic out for the hallucinogenic spores.