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This may sound silly, but I can honestly see James and Ash being sort of a representation of each other. Now of course one is a protagonist and the other the antagonist but when you look at the bigger picture they really aren't that much different.
>Both care deeply for their Pokemon as to go as far as to almost kill or injure themselves to save them
>The best fighters of their teams
>Pokemon shown to have deep emotions for them
Also, I can see that since Ash can go "Mega Greninja", I can also see James with a "Mega Arcanine" given if he decided to evolve Growlie at home, since he has a very strong bond with it since he was a child. It'd be great to see James leave TR and start his own journey, maybe become a rival for Ash too.