>>28248404Just like animals in the real world, this is going to vary species to species, and heavily with experience. The vast majority of wild Pokemon do not train very much, spending most of their time either gathering food, patrolling their territory or taking care of their young. A wild Rattata or Sentret might badly injure someone if they felt inclined to attack a human (which is rare), but one solid hit from a lead pipe is going to put that Pokemon out of commission. A decently in-shape adult human could potentially overpower most smaller/frailer Pokemon through physical strength alone, but considering that practically all Pokemon are gifted with a variety of natural weapons, attempting to wrestle down something like a Raichu or Servine is seriously ill-advised.
With evolved Pokemon, and trained Pokemon in particular, this becomes another story. An attack from something like Giovanni's Rhydon or Lance's Dragonite could very well turn your average 10 year old Pokemon trainer into mincemeat, and their natural armor makes their body as tough as granite. Anything short of a large caliber rifle round is not going to injure a Pokemon that strong, which makes them phenomenal bodyguards. That being said, not even the most powerful Pokemon alive can shrug off heavy duty military ordinance, and almost all human governments have special forces specifically trained to neutralize dangerous Pokemon should they prove a danger to the public.