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Dragon, obviously. Every dragon except 5 are in OU or Ubers now. Water's a close second too, especially with Asshole Politoed up in OU.
In Gen 6? Ghost will dominate this gen now that Steel doesn't resist it anymore. Ghost/Fairy will be a scary combo, and at least one mon might possibly get it through retcon. Dragon itself is worse, though Garchomp and Salamence and co. will likely still be OU. Water's still OP as fuck unless GF does something to balance Drizzle (>implying they will)