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Hilda's design parallels N very well, with her black over white sleeveless and high ponytail complimenting N's low ponytail and white over black long sleeve. That said, most of Pokemon feels like it was made with male protag in mind.
>Red and Ethan obviously had no feMC counterpart until later revisions and remakes
>Brendan's house position mirrors Red's, his Japanese name, Yuuki, was originally Yuu in early material as in (You)
>Lucas heavily used for early promo material of DP, with Dawn being relegated to the girl they sometimes use (they fucked up here considering how popular Dawn was in the long run compared to his dorky design and backpedaled later)
>Shauna was explicitly stated by Masuda to be shipbait with the protag for XY. That said, a lot more effort went into customization for Serena.
Meanwhile BW2 only works with the context of opposite gender protag from the previous game. As Nate, NPCs from Hilda's run show up, while NPCs from Hilbert's only show up if you're Rosa.