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>Red Nuzlocke
>but the first Pokémon encountered in an area may only be caught if it's a Poison-type
Not first Poison-type in an area; if the first Pokémon in an area isn't a Poison-type, that means I don't get anything from that area.
Is this practically doable, or am I setting myself up for failure? Do note that HM availability is guaranteed, since the Bulbasaur line learns Cut, you can buy a Nidorina at the game corner for Surf and Strength, while neither Fly nor Flash is actually required to progress.