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Open world. Get rid of IVs. Make nature boosts changeable and independent from the flavor text. Make editing your moveset easy and on the fly (at any Pokémon center). No heartscales. No bottlecaps. No grind.
Open world. Choose your own adventure. No focus on plot. Complete trainer customization (body type, age, height).
A return of dungeons. Difficulty sliders. Pokémon Stadium-esque postgame. Sex minigame.