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Somebody requested a difficulty tier list for fangame nuzlockes a while back. Decided to draw a rough draft of them up, based on personal experience, what I know, what I've played, and from what I've seen (a lot from this last bit, as I haven't played a lot of/successfully completed a lot of the games on this list). These are also roughly tiered within each tier. These tierings are mostly based on you, the player, not just doing things like cheating in 999 Rare Candies from go or spamming items (though that is kind of a necessity in S tier). Basically:
S Tier - Absolute sanity ruiners, completing nuzlockes of these games will be some of the hardest things you ever do.
A Tier - Among the hardest hacks in existence, but on the cusp of doable.
B Tier - Several notches above average difficult hacks, but relatively manageable.
C Tier - Where most 'harder' fangames tend to sit, team compositions are generally much better than the main games but not vastly so.
D Tier - About on par with if not even easier than the main games in some cases.
Might do write ups for all of these in the vein of what /nuz/ organized for the main game difficulty tier rankings. If anybody who thinks the tierings are wrong feel free to contest them, I do think a lot of these positions could probably change