>>14714346Not that guy, but I feel like there's enough evidence to at least make a solid argument for Team Rocket making Mewtwo.
They first appear in-game trying to clone Fossils, so they knew about cloning from "somewhere" (Mewtwo).
After that fell through, they went after Ghost types to help catch the abomination they are super effective against. That went to shit. They also abduct Fuji, so they must have a history with him.
Once that's all nackered, they bullrush the Silph building to get a Masterball as a last ditch effort to capture the Purple Franken-Fetus.
Makes sense to me. Otherwise it's a pretty big coincidence.