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Disgustingly long multiple-post incoming (don't worry, I'll sage myself)!
UK Region guy here! Here's an MS Paint version of my region map. I've called it Breto for a couple of reasons, obviously it sounds like Britain but also it keeps "o" in the name that's an unusual tradition in all English language Pokémon region names so far! So, let me talk you through it.
Black lines are regular routes, blue lines are water routes and green lines are back-track routes that open up after you have the appropriate badges. Red numbers denote route numbers. Gold locations are important locations along your journey, including locations in the Gym Challenge. Purple locations are places of note that are housed along routes. Blue locations are places that make up the route themselves. Pink areas open up in the post-game after certain criteria are met.
Brumam Town is where you begin. Birmingham is known as a hub of education, I was pleased to discover, as that made it an obvious choice to house the Pokémon Research Laboratory and the start of the game.
Notnam Forest is, of course, based on Nottingham Forest and sees mini-boss Forest Lord Robin challenge you if you can beat his Merry Fellows.
The Warped Spire is based on Chesterfield's Crooked Spire, the most famous landmark in Derbyshire.
Sheffel City is an industrial city based on Sheffield, with the Steel-type being highly heralded as Sheffield is famous for its steelwork.
Newcle is based on Newcastle, a well-known mining city and the Alexandrina Mine is the cave leading into it, based on Victoria Mine (Alexandrina being Queen Victoria's first name). The Twin Angel statues replace the Angel of the North- giant statues of Latios and Latios that play into the game's story.