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A family member got a 3DSXL. I've tried playing it before, but with the exception of bottom-screen DS games, it's an absolute pain to play. My hands are average size and my fingers somewhat short, so at first it's totally fine but the cramping kicks in after only a minute. Street Fighter is nearly unplayable. It's not so much the size of the system as the size combined with the simplistic shape combined with the weight of the system.
I want to buy a 3DS myself, since I do like the 3D and being able to close the system. And I don't think the cramping will happen. Yes big screens are cool, but whatever.