>Gen 1
"Use Clefable. It's a better version of Wigglytuff."
>Gen 2
"Wigglytuff has a great movepool, but is out-shined by Clefable in every way. It doesn't have a recovery move, and it can't sweep with Belly Drum like Clefable can. Wigglytuff is decent in UU, however, because for the most part, move versatility is more important than attack strength. Even so, Clefable can play the attacking game better."
>Gen 3
"Clefable is generally a better Pokémon, because he has better stats all around (better defenses, Special Attack, and Speed in trade for worse HP) and is even more versatile with Encore, Meteor Mash, Belly Drum and a few other moves."
>Gen 4
"When it comes to defensive Normal-types, Wigglytuff definitely isn't a popular choice in UU, as she is horribly outclassed by Clefable, Chansey, and Lickilicky."
>Gen 5
"Wigglytuff is a depressing case of a Pokemon. Since its inception nearly 15 years ago, its mediocre stats and the mere existence of Clefable, Chansey, and even Lickitung had doomed Wigglytuff into complete obscurity."