Fuck no.
But IF it happened, this is how it should go down:
First off, no taking characters from the anime. Maybe a homage or two, but that's it. New characters. Not overly cheesy, but not ultra grim dark either. Plot could be a villainous organization (preferably Team Rocket, or something similar) trying to harness control of powerful Pokemon.
Now it could split here, but I would prefer if they made the Pokemon look realistic as fuck. No cartoony bullshit like in the OP image.
Make it less about "fighting to be #1" and all this crap, rather about the wonder and spectacle of the universe with these amazing creatures. But then of course bring in the villainous plot line too. Also personally I would want Pokeballs to be ditched entirely, but of course that wouldn't happen.
Annnd in my mind it would all work better if they were merely referred to as "creatures" or "animals" rather than "pokemon." It's essentially Earth V.2, but with ultra awesome animals (some with magiiikal powers) instead of the pleb shit we have today.