gained the most:
charizard, kangaskhan, pinsir, heracross, gardevoir, mawile, manectric, medicham - once the dust settled, their megas catapulted them straight up from lower tiers to ou/ubers
bisharp - knock off buff, steel nerf means it doesn't need to run superpower/low kick any more, gets a free +2 on a predicted defog, is unaffected by king's shield
azumarill - fairy typing, new breeding mechanics make belly drum + aqua jet legal
clefable - fairy typing and bst boost shot it up 2 tiers instantly
suffered the most:
alakazam - only 90 bst gained as a mega, loses magic guard for the highly situational trace, mega is less useful than life orb and focus sash variants, steel nerf made its weaknesses far more common
metagross, jirachi - meteor mash nerf, steel type nerf gives them 2 new weaknesses to now common dark/ghost type moves
hydreigon - forced to run flash cannon or get walled forever by fairies, gets ohko'd by em anyway