>>21401204January 22, 2027: Dr. Hagiru Sato and his team of scientists from Japan, America, Canada, and Britain begin work on a matter-energy transference machine.
February 11, 2033: First machine is tested successfully after over a hundred failed tests. Controversy over the destructive nature of the technology ignites.
July 18, 2033: A catastrophic incident with an energy-matter machine destroys the city of Hiroshima, in devastation not seen since the atomic bombs were dropped nearly 90 years prior. Japanese government officials move to ban work on this technology, though Western powers urge them to allow it, despite the mishap.
April 22, 2035: First sighting of infected individuals. Most are animals, some humans are also shown to be susceptible to infection. Most seen around the ruins of Hiroshima, which had not been rebuilt.
May 13, 2035: Northern Japan is split off from its southern half as a nation-wide quarantine is enacted. Anarchy soon spreads through the infected regions. 15% of humans exposed to the disease are immune and show no side effects. 84.9% are affected fatally by the disease, which causes cancerous growths. 0.1% of those exposed are shown to successfully mutate. The "virus" is found to be a spreadable corruption of genetic material, which causes rapid mutations in infected individuals. All large animal life is soon infected.
January 1, 2040: 98% of all animals in Japan are wiped out; ecosystems ruled entirely by infected individuals.
May 8, 2048: Japanese Defense Force engages infected individuals to preserve quarantine. Co-ordinated attacks by infected humans and animals are seen. High levels of intelligence confirmed.
May 10: They fail, and the nation of Japan ceases to exist.