>>23502537Running a game right now.
Keep lots of notes on moves and stuff. Every move that any pokemon can use should be on a notecard somewhere that you can get to easily, otherwise combat will take forever with you constantly checking the pdf.
Use the pokemon league. In fact I would highly suggest using a canon region with very few changes outside of story, as a DM this will help you immensely.
Combat is a large portion of the system and will get dull eventually. Shake it up by adding more dynamic fields. In my last session they fought in a field on a floodplane that was slowly getting washed out, limiting their movement and putting them on a timer.