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My tabletop group is currently doing generic-medieval-campaign-but-with-Pokémon in the PTU system, it's been fun. It's a small game, just two players and the GM, both PCs are trainers with mystic powers since the setting makes it less Mary Sue-ish than it would otherwise be, an Oracle with a focus on Dragon-types inspired by Zinnia, I hate the character in ORAS but I like the concept and a Hex Maniac with a focus on, well you know. Gathering the type-based MacGuffins because an ancient evil awakens, standard stuff.
I want to GM a PMD-themed game one day but I'm too much of a perfectionist to ever get my materials for the campaign up to snuff, probably won't ever happen. If it ever does it'd be a pretty standard setting for that kind of thing, with rescue teams and such. I'd never feel comfortable doing a game like that outside my group though since there are no furries in my group well there's one but he's never tried to push furshit into any of our games, not even when he GMed once, so I trust him enough. PMD seems like a furry magnet, I love the games but you can't talk about the series on /vp/ ever since they made that general and it got filled with people writing lewd fanfics about their parties.