>>26915282My illness affected my school performance.
Poor grades are an effect of illness.
He tried to help defuse his friend's anger to no effect.
He could not affect his friend's temperament.
I am affected by your aggression.
Your aggression affects me.
Your aggression has a significant effect on me.
The effect of your aggression on me is significant. (Effect is being talked about as an object/noun/subject)