How would you feel if after Sun and Moon, Gamefreak brought us back to the Kanto region? It wouldn't necessarily be a remake, but instead be a psudo-sequel. The game would have the same towns, gyms, and general map layout as Red and Blue, but it would also have a totally new story, new gym leaders, characters, etc. Think what Nintendo did with A Link Between Worlds and A Link to the Past.

Maybe even make all the new pokemon inspired by Gen 1 designs to encounter alongside the old Kanto pokemon.