It could, I guess. Canonizing glitches like that isn't unprecedented: the first thing that comes to mind is Ermac from Mortal Kombat. In turns of "Genwunner pandering", Missingno. is probably the biggest thing - aside from maybe a "Mewthree" - that they haven't milked yet.
I doubt it's something they'd ever do, though. They've never even alluded to it before, other than Nintendo first addressing the glitch when it was discovered, and there's no real precedent for anything like that in Pokemon. There was that Mirage Master movie that seemed to have been inspired by hacked Pokemon, but at least as far as the games are concerned, nothing quite so self-referential. I'm not sure how popular the Missingno. glitch was in Japan, but I've heard before that it wasn't as well-known over there/more popular in the West, so I'm not sure how on-the-radar it is for them. But you look at things like Ultra Beasts and Silvally, and it's pretty clear that they're trying to do challenge the preconception of what a Pokemon can be. But they've always been pretty wary of glitches and exploits, so I'm not sure how likely it is that we'd ever see Missingno - or at least some self-referential "glitch Pokemon" - being canonized. In the very least, I think it's something that, if they did, would garner a lot of attention.
