Here's where we go from here - the next game(s) is a sequel to Sun/Moon set in Kanto.
Kanto's been remade so it's like the newer, larger regions. The protagonist meets Lillie early on, gets a Pokemon, and she tells you about Ultra Beasts and shit and how they've started appearing in Kanto and she's investigating.
Shortly after, she fucking disappears - kidnapped by Team Rocket.
Over the course of the game as you investigate her disappearance, you realize that the Pokemon League, Silph Co -- all of that is owned and financed by Giovanni. He's worked in the shadows quietly to build his empire, and now he owns fucking everything. The gym leaders, elite 4, all of them have been replaced with people hand picked by Giovanni.
So the plot of the game is twofold - you want to find Lillie and figure out what the fuck is up with Giovanni using Silph to research Ultra Beasts, and you also want to dismantle his empire by becoming champion and reshaping the E4 as you see fit.