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As someone who runs Mandi in competitive a lot, the best set is generally
Mandibuzz @ Leftovers
Ability: Overcoat
EVs: 248 HP / 136 Def / 108 SpD / 16 Spe
Bold Nature
- Foul Play
- Roost
- Taunt
- Defog
I know it's the standard set, but it's fucking amazing. Unless you're packing some seriously powerful coverage you're not killing this thing, Taunt+defog makes it a great anti lead