Mewtwo is a Pokémon that was created by genetic manipulation by recombining Mew's genes. However, even though the scientific power of humans created this Pokémon's body, they failed to endow Mewtwo with a compassionate heart. His cold, glowing eyes strike fear into his enemies.

Mewtwo's extensive foreskin and large ball sac betray his origins as a scientific monstrosity: a dream to create the ultimate Pokémon. Mew's fine, pink hairs have been lost as a result of the program, leaving Mewtwo's willy as bare purple skin.