>Red and Blue are rebooted in a similar way to HGSS's style jump from DPP.
>Characters, areas, and events are different in each version. (Red features a Young Oak, while Blue has an Old Oak, Pewter City is covered in Snow in Blue, a "Desert" in Red).
>Villain team isn't Team Rocket, but a new team based on the color Green/Purple.
>Player is a redesigned Red and or Blue(Female).
>Box Legendaries are "Legend" versions of Charizard, Blastoise, and Venasaur.
>Story revolves around a Unique Charizard or Blastoise(depending on version) that have a Legendary Status and stats to match.
>Legend Venasaur is the Trio master, Grass/Electric an Ability that makes it immune to Fire attacks.
>Legendary trio is based on Zeus, Hades, Poseido(Bird, Dog, Sea Serpent).