>>37045763I remember seeing a blind player playing Pearl, using small cues such as the sound effect for hitting a wall and the different cries for almost every pokemon, along with a lot of memorisation, so it's evidently not completely impossible. I'll have to see if I can dig that up.
Ignoring this extreme, though, Pokemon is one of the least physically demanding games that exist. The overworld movement is as demanding as it gets, and that's not exactly asking for much. Because of that, I think it's fair to expect Pokemon to keep its probably larger-than-average physically
and mentally disabled playerbase in mind.