>>37225428>>37227132>if they had enough firepowerWhich they don't. Most fully evolved Pokemon are city level threats. Tyranitar, Machamp, Gyarados, even Gigalith, know what all those have in common? Every one of them can casually output more energy than a nuke. We still have to discuss NFEs, but I don't see how you'd be any better off against them. The fact that Onix, a thirty feet long snake made of boulders has one of the worst attack stats in the game should say it all. Or that Mach Punch and Bullet Punch - the description for both of which states they break the sound barrier, making them much more powerful than any handheld gun - only have 40 BP.
So yes, you could maybe down a NFE Pokemon if you were sitting in a tank. But only NFEs. And good luck fighting anything hand to hand or with a gun. Even the weakest Pokemon attacks would completely overwhelm real life humans.