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Presumably it's the protagonist with access to most Pokémon, even through trading or transferring.
>Gold/Ethan, Kris, Lyra, Nate, Rosa, Elio, Selene, Chase, and Elaine as players can beat NPC Red
>Elio/Selene can use everything Brendan/May can use everything Calem/Serena can use everything Nate/Rosa can use everything Hilbert/Hilda can use everything Ethan/Lyra can use everything Lucas/Dawn can use everything Red/Leaf can use everything Kris can use
USUM > ORAS > XY > B2W2 > BW > HGSS > Platinum > FRLG > Crystal
There are a few asterisks.
>Not all move sets possible from Crystal can be used up through ORAS
>A handful of Pokémon have had their abilities changed between Gens, like Gengar losing Levitate, but usually the benefits of all the other new Pokémon and mechanics outweigh the potential drawbacks