Let's compile a list of every possible feature we can think of that was nerfed/removed on the transition between gens (as well as enhanced games).

Obviously, Gen I is useless to do because Yellow didn't remove anything from RB(G), so we'll start with the things removed from the Gen I to Gen II transition.

Feel free to discuss, criticise any suggestions and obviously to suggest as many as you can. When we reach Gen 3, we can also compare remakes to their originals. Now:

Gen I to Gen II
>No more starter Pokémon following you.
>No more Safari Zone.