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Only when they're interesting, which most of the time they aren't. Fuck, the only girls in the entire series that I could remotely give a shit about are Cynthia, Lusamine, and Opal and that's because they have some sort of say in the lore. Most other women are mindless waifubait that are either forgotten by the time you battle them or do nothing but suck your dick.
Pokemon is a world that can introduce interesting human characters, but the creatures themselves are what makes the setting unique and everything about the story and lore should be built around them.