>>46207219Most JoJo characters are at Batman levels of fitness. DIO, using Jonathon's body, is capable of picking up a whole ass road roller and jumping with it. King Crimson can cleave a body in two by itself, and character in JoJo are notoriously resilient.
I'd assume that, if Mewtwo had no psychic barrier that repelled King Crimson, King Crimson could chop Mewtwo in half. That's assuming Diavolo can get within 2 meters of Mewtwo in the first place. If everything goes well, Diavolo would win, but I think 7 out of 10 matches would go to Mewtwo.