>>50455474Of course, they're completely different characters with different personalities and motivations. I really don't think there's anything they have in common outside of their appearance and even then that's just for ashnime Serena's initial design (which is an altered version of game Serena to begin with). They've changed her so much with redesigns after that they don't resemble each other in any significant way at all.
I basically view ashnime Serena as Yajima making a pre-planned OC but using the gen 6 protag as a base rather than adapting the game character for the anime.