>>50451555No, this has a 0% chance of happening. You really underestimate how obsessed Japanese people are with seiyuu, they are pretty much idols in their own right. There is a reason why most of the budget for anime is spent on seiyuu salary. They are basically tied to those characters and Japanese people think it's not the character if it's not the original voice actor.
Unless she dies, it's not happening, and even at that they'd just formally retire her because she's not a main character anymore. The only times I've ever heard of this happening is if a major character's seiyuu dies (and only of old age) and there was a character from Bandori who's seiyuu retired from voice acting less than a year after taking the role (so when Bandori was still small and irrelevant).
It's just never going to happen, sadly. Your best hope is if they do an AU or reboot or something so it's technically not the same character anymore.