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Pretty sure the only trainer that gave me any trouble at all was Nemona at the every end and only because I was on autopilot setting up in her face and then she haxxed the fuck out of me with a crit which fainted the pokemon I was setting up with, a freeze on the next one I brought in, another crit to faint that pokemon, and a muddy water accuracy drop on the next pokemon I brought in which did matter because I missed on her next pokemon twice which let her almost knock out mine.
Outside of Nemona's insane hax, I don't think any other trainer was even close. Maybe Clavell? His water tera'd Quaxaval was actually kind of scary just spamming Aqua Step, but Water Absorb Clodsire put a stop to it.