>>57415521Pretty much any region with close cultural ties to their legendaries would be hard to subdue.
>Johto, Hoenn, Kalos, GalarPatriotic, but probably still reasonable enough to negotiate with (as long as you don't fuck them over). Most of their legendaries are dormant or rarely seen, so they play more into the region's founding myths and establish its inhabitants' identity.
>AlolaLikely more fundamental, as the guardian deities (Tapus) are more present. But probably not in an offensive, but defensive way. Stay off their lawn, and you will be fine.
>SinnohLikely to descent into fundamentalist fanatism, see
>>57415536>KantoProbably atheistic, the legendaries don't appear to have that much of an cultural significance. The birds just exist, Mewtwo is a top secret experiment and Mew is a myth.