>Johto (HGSS)
-Looker and other policemen appear investigating the Rocket Hideot in Mahogany in the postgame in a little event where he gives you some rare item.

-After the Shinjoh event, Cynthia appears every Sunday noon in Alph Ruins and you can fight her.

>Unova (B2W2)
-Looker BW event stays the same. In B2W2 he appears arresting Zinzolin on his own and gives you the Abyssal Ruins research so you can investigate for him what Ghetsis and Zinzolin were planning.

-Cynthia her event stays the same

>Kalos
-Looker event stays the same

-Cynthia appears in Tower of Mastery every thursday because she is training the use of the her new Garchompite (here also appears Leaf and Mega Venusaur on monday, Silver and Mega Tyranitar on tuesday, Noland and Mega Aggron on wednesday, Shauna and Mega Mawile on friday, Trevor and Tiermo and Mega Aerodactyl and Mega Medicham on Saturday and Korrina and Mega Lucario on sundays)

>Hoenn (ORAS)
-Looker appears the same but with his coat thorn and wearing a Pearl Clan outfit under it

-Cynthia appears after the Delta Episode in the Granite Cave along Steven investigating the ancient mural there. You can have a double battle against them there (highly difficult battle, both use megas, you get the metagrossite and garchompite if you win)

>Alola (SM/USUM)
All the same

>Kanto (LGPE)
-Looker is the interpol agent in SS Anne

-Cynthia also is in SS Anne, she is on a vacation and she gives you an item.

>Galar
-Looker will appear in Spikemuth to get an autograph from Piers, he is a big fan.

-Cynthia appears investigating the treasure of the Hammerlocke Vault in postgame. She will ask you to battle (she dynamaxes her Garchomp), after you win, Raihan will appear angry and will kick out both of the stadium for battling without permission.

>Hisui
-Looker takes the place of Ingo (to link with his mystery appearance in ORAS)

-Cynthia has no direct appearance, just her ancestors are present