>>58850454The Teraleak.
Pokopia started its development life as a spiritual LGPE successor (an ultra-casual gen 1-centric game) and as development continued, they soon settled on the idea of the setting being a Kanto that fell victim to environmental collapse, an expected consequence of the region's continued industrial growth with no regard for the environment.
This isn't a disaster in the sense of nukes of war, it's an environmental crisis that forced humanity to flee while leaving the Pokemon to deal with the consequences, and humanity's been gone long enough that everything's fallen into ruin, been reclaimed by nature, or is still being scarred even to this day.