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It all really comes down to these 3 simple things
>right place
>right person
>right time
She went super viral after the 2020 clip of her discussing her illness.
Said clip got her noticed by Project Melody, who included her in collabs and got her signed onto VSHOJO, which was just a front for indie groups to have legal and merch assistance at the time.
Got noticed by Connor and would constantly collab with him, getting the attention of normfags near and wide.
More collabs and events with other well known indies and big corpos such as hololive.
and to top it all off, had a record breaking substhon in 2022, which brought even more eyes far and wide to see what the most twitch subscribed anime girl streamer was about.
She had a golden opportunity handed to her and used it to her full effect, networking and turning her small channel into a well known brand,not really that complicated.
Pipkin Pippa pretty much blew up in the exact same way if you want another example.