>>6687709She has, and literally made sure to never look at chat until it got to the absolute last bit of a puzzle she was brute force memeing at. She opened up chat for just a bit and while she was reading out some genuine hints, most of the chat was just typing "TYPE [answer]" and after noticing the same answer appear several times she got annoyed and just wanted to get the stream over with. Also a spam bot showed up around the same time she opened up chat for real.
I think the problem is unlike Ame, who doesn't particularly care about her chat too much when streaming, Reine seems to enjoy reading her chat if her forcing herself to stream when sick was any indication. It's just she gets fucking annoyed that all the back seating makes interacting with the chat impossible during puzzle segments, as if Reine hasn't proved she can handle most logical puzzles.