>>7181414>>7181536>>7183412Some Compacts and Conspiracies make good use of hunters who turn into monsters, but those have the backing to watch them constantly and have a good Destroy Immediately solution if they turn rogue if we're talking Conspiracy level.
A player does have options for their characters to turn into some sort of supernatural thing without looking like an abomination, as there are Mortal 'templates' like psychic powers, the atariya, etc.