>>51092448I'm personally writing Lui to be a major recurring villain in my story but major as in just in number of appearances, because as far as plot goes, she doesn't influence much. Chloe holds basically zero final boss power unless you're Kojima and developing Death Stranding 2. Koyori might have potential but you'd really have to lean into a mad scientist archetype which would be very silly. Iroha has big boss potential, but only somewhere around middle of the story. Laplus... there's a lot you can do with her, but as far as taking her as a boss, you'd need to go a lot into OC unshackled Laplus territory to pull anything off with her.