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Usually men are pretty easy to sway (just act virginal, youthful and sexually available) yet somehow Twisty just can't get you guys on her side.
I wouldn't really call her a pickme since she doesn't accept poor treatment from men, but she's clearly the kind of girl who wants to be "one of the guys", and it's sad that she can't really seem to achieve achieve that. I do hope she can eventually find an audience and rid herself of the brainworms that plague her.