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>In test tube studies of nasal cells infected with influenza, exposure to the female hormone estradiol reduced the immune response when the cells came from women, but not in cells from men. Treatment with antiestrogen drugs reduces this effect. Since flu symptoms are in large part due to the body's immune reaction, a lessened immune response in women may translate to milder symptoms.
So men may not be acting when they have the flu, but actually experience it more severely than women