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EN will very likely at least be bigger than KR and ID and they seem to be perfectly fine with those two branches, so unless your expectations are at HoloEN levels (in which case lmao) then no, there's no indication of them being "doomed" as in the branch outright failing. It'll likely have more of a side project status unless there's some unexpected visibility explosion, but it's a very safe side project.
I'm more curious what they'll do with it, if they're gonna do something weird or unexpected against Hololive playing it super safe. One good shot they could have is getting into the western male vtuber market since Kanae and Kuzuha are probably the most clipped Nijisanji vtubers right now and Holostars is a joke.