>>57156157When it comes to the pixelated look, the biggest difference is antialiasing, it's usually a setting somewhere and it smoothes the edges. Many details when it comes to brushes seem to differ between software, some of the higher end programs have actual paint simulation, I use krita and it doesn't. Honestly, brushes are sort of over my skill level, because I'm used to pencils so I just experiment with whatever, but I like having pressure tied to opacity, it makes blending colours easier. If you have any specific questions I might try answering them, but if I start talking broadly it's going to turn into a wall of text.