>>69263305Your winning hand will always be 4 groups and a pair, so being able to look at your hand and break it up into blocks you can focus on to reach tenpai is a key strategy.
Additionally, certain tiles in your hand are more likely to get improved into blocks than others. An isolated honor tile has bad acceptance because you need to draw the same tile yourself to turn it into a pair, but a 4m tile has good acceptance because it can get improved into a block after drawing one of 23456m. As
>>69264106 says discarding isolated honors first, then terminals, then number tiles closest to the edges is a generally good strategy for maximizing the number of future tile draws that'll improve your hand.