>>48601096I'm honestly not a huge fan of how R-ESRGAN Anime6B works on its own - it tends to create lines that are too thick and smooth compared to the original image. Especially if you're using it with AOM2 or 3 - it destroys a lot of the film grain-ish texture that makes gens from those models look so unique.
I usually get the best results by using the WebUI upscaler with Lanczos as the main upscaler and then R-ESRGAN Anime6B as the secondary one with visibility around 15-20%.
Pic related - here's a comparison of the original and running it through the various upscalers:
Original:
https://files.catbox.moe/zip017.pngR-ESRGAN Anime6B only:
https://files.catbox.moe/iowa4z.pngLanczos only:
https://files.catbox.moe/lj1dig.pngLanczos primary, Anime 6B secondary with visibility 0.15:
https://files.catbox.moe/rc9gbg.pngYou can see how Lanczos alone looks blurry and blatantly upscaled, while Anime6B alone looks too clean compared to the original, but mixing them preserves the look of the original really well.