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Reviewing the formations, the center-focused formations such as /yah/, /hfz/, and /yubicraft/ do have higher center attack bias, however this seems to be a quirk of PES '21, as EVERY team has a high center bias, with only /towa/ and /koopa/ having a sub-40% average center bias.
I ran a few scatterplots in an attempt to find a trend, but there's not enough data to run on. There's a very rough trend indicating center bias will result in more points scored, but it's too rough to be conclusive.
T-Test indicates the possibility of a correlation between center bias and scoring points.
That said, I wasn't joking when I said this shit is above my pay grade. Futbol is a game, but it's not within my area of expertise. Take this data with a grain of salt.