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So based on things Aqua herself, Marine and others said, the reason probably is:
>Hololive becoming really big and focusing even more on the business and idol side
>2022 with the end of covid and everything opening again, so aqua had to go in person for meetings and recordings instead of being able to stay in her room streaming and playing games all day
>The perms hell making impossible for her to play everything she wants
>6 years doing the same thing, doing things she don't actually wanted finally got to her
So yeah, it seems it was basically the terminally recluse Aqua not being happy with the direction Hololive was going and decided to stop now because she felt bad for her fans since she wasn't giving her 100% for all the support she received